ODCs

Cytoscape Web

Click node...

Dedifferentiated liposarcoma

3 associated genes
No signs/symptoms info

PROTEIN INTERACTIONS: 2

Lethal acantholytic epidermolysis bullosa

1 OMIM reference -
2 associated genes
10 signs/symptoms

Dedifferentiated liposarcoma

Lethal acantholytic epidermolysis bullosa

CDK4	(UniProt - OMIM)		DSP	(UniProt - OMIM)
HMGA2	(UniProt - OMIM)		JUP	(UniProt - OMIM)
MDM2	(UniProt - OMIM)


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	MDM2 MDM2	(0.63) (0.63)	DSP JUP

Citations in the biomedical literature:

Dedifferentiated liposarcoma		Lethal acantholytic epidermolysis bullosa
	Synonym(s): - DDLS		Synonym(s): - LAEB

	Classification (Orphanet): - Rare oncologic disease		Classification (Orphanet): - Rare genetic disease - Rare skin disease

	Classification (ICD10): - Neoplasms -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: adulthood Average age of death: adult Type of inheritance: sporadic		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: before age 5 Type of inheritance: autosomal recessive

	External references: No OMIM references No MeSH references		External references: 1 OMIM reference - 1 MeSH reference: C535493

Lethal acantholytic epidermolysis bullosa
	Very frequent - Absent / small fingernails / anonychia of hands - Alopecia - Autosomal recessive inheritance - Chronic skin infection / ulcerations / ulcers / cancrum - Early death / lethality - Enanthema / aphtosa / aphta / leukoplakia - Premature eruption of teeth / natal teeth - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment Occasional - Cardiomyopathy / hypertrophic / dilated - Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis
Dedifferentiated liposarcoma
(no data available)